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Medical News Today: Health News
How can seafood help curb heart ailments?
G Ramanarayanan | Sun, 02 Mar, 2008,12:42 PM
It is known that Eskimos are good at catching and eating fish, whales and polar bears. Despite eating a diet high in fat and cholesterol, Eskimos have very little coronary artery disease incidence. How can this be? A clue may be found in other characteristic of Eskimos, their marked tendency to nose bleeds and other bleeding problems. . Here we learn more about the importance of the nature of the fat we eat and about the important rule that clotting can play in coronary artery disease. Peter O Kwiterovich from the famous John Hopkins Institute writes: ‘The best way to slash your chances of heart disease, is above all to eat fish, particularly fatty fish, overflowing with Omega-3-fatty acids. 'The evidence of fish’s preventive and therapeutic powers against cardiovascular diseases is compelling. Seafood is heart medicines, it’s unique marine fat, so, fish may be the one food where fat is healthier.’ Fish Oil: Sardines, mackerel, tuna, salmon and herring (fresh, frozen or canned) are the fish and shell fish, either from their flesh and fatty tissue or from certain organs such as the liver. These fats are different from the fats in animals. There is a wide variety of fatty acids in fish oils. Two are especially rich - EPA Eicosa Pentaenoic Acid and DHA Docosa Hexaenoic Acid. EPA and DHA are both polyunsaturated fatty acids and they are known as Omega-3-fatty acids. Both EPA and DHA appear to provide protection from cardiovascular disease by decreasing the bad fats in the blood and increasing the good ones. The ways in which fish oil fights heart disease to be really scientific * Blocks the platelets aggregation (prevents blood clotting): * Reduces blood vesselconstriction * Increases blood flow through arteries * Lowers a blood-clotting factor known as Fibrogen’ * Boosts up fibrinolytic (clot dissolving) activity * Lowers good HDL-cholesterol * Lowers high blood pressure * Makes cardiac cell membrane more flexible * Wards off deadly fibrillation (irregular chaotic heartbeats) Fish oil and red blood cells Fish oil may also help making the red blood cell (RBC) membrane more flexible. The more flexible the RBC, the more easily it passes through the tiny capillaries. This had potential importance for diabetic kidney disease and diabetic stroke individuals. For proper kidney and brain function, RBC’s must be able to pass through the tiny capillaries of the kidney. Fish oil and coronary artery disease Greenland Eskimos as observed by researchers 15 years ago had a significantly lowered rate of coronary artery disease than Eskimos who lived in Denmark. The diet of Green Land Eskimos consisted almost entirely of marine products: the average adult Eskimo consumed 16 ounces of fish per day. Japanese living in fisherman’s islands, who ate an average of four ounces of fish per day, were found to have lower rate of coronary artery disease than Japanese in urban areas. It was found in Netherlands (reported in New England Journal of Medicine). After 20 years of consumption of fish of 1 to 1-1/2 ounce per day, death from coronary artery disease was 50 per cent lower in those men who ate fish. Eating an ounce of fish a day or a couple of servings a week, slashes your chances of heart attack by 1/3-1/2 studies show. Eating fish food will reduce the chance of blood clots and prevent heart attack and stroke, Dr N Vetrivel says in his book Healthy Hearty, is a Matter of Personal Choice.
News Today - An English evening daily published from Chennai
'2-Faced' Particles Act Like Tiny Submarines
Main Category: Biology / Biochemistry
Article Date: 02 Mar 2008 - 6:00 PST
For the first time, researchers at North Carolina State University have demonstrated that microscopic "two-faced" spheres whose halves are physically or chemically different - so-called Janus particles - will move like stealthy submarines when an alternating electrical field is applied to liquid surrounding the particles.
A paper describing the research, published in the Feb. 8, 2008, edition of Physical Review Letters, advances knowledge about how potential "smart" materials - think of tiny engines or sensors - can move around and respond to changes in their environment. Janus particles could be used as microscopic mixers, molecular "shuttles," self-propelling microsensors or means of targeted drug delivery.
The researchers - Dr. Orlin Velev, associate professor of chemical and biomolecular engineering at NC State and lead author of the paper; Sumit Gangwal, an NC State graduate student; Dr. Olivier Cayre, a post-doctoral researcher in Velev's lab; and Dr. Martin Bazant from Massachusetts Institute of Technology - created tiny two-faced gold and plastic particles and applied low frequency alternating current to the water containing the particles. The electric field was of voltage and frequency similar to the ones you'd get if you plugged a device into a socket in your home or office.
Velev says the micrometer-sized particles convert the electrical field into liquid motion around them and then unexpectedly propel themselves perpendicular to the direction of the powered electrodes - not in the direction of the electrical field, as would be expected. The particles always travel in the same orientation: with the plastic "face" as the front of the mini-submarine and the metallic "face" in the rear, Velev added.
The phenomenon - called "induced-charge electrophoresis," which had been predicted in a theoretical model by the MIT collaborator - had not been demonstrated previously.
The term "Janus particle" comes from the name of a Roman god with two faces. Velev says that these materials have the potential to perform a variety of applications.
"You can imagine other types of Janus particles comprising a 'smart gel' that responds to a change in its environment and then releases drugs, for example," Velev says. Fabricating these responsive materials on the microscale and nanoscale is an exciting and rapidly developing area of science, he adds.
"We are able to create tiny Janus particles of the same size and shape and are beginning to learn how to give them functionality," Velev said. "The next step is to create more complex particles that are able to perform more specialized functions in addition to propelling themselves around."
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Article adapted by Medical News Today from original press release.
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The research is funded by the National Science Foundation and a Camile and Henry Dreyfus Teacher-Scholar grant.
The abstract of the paper follows.
"Induced Charge Electrophoresis of Metallodielectric Particles"
Authors: Sumit Gangwal, Olivier J. Cayre and Dr. Orlin D. Velev, NC State University; Dr. Martin Z. Bazant, Massachusetts Institute of Technology
Published: Feb. 4, 2008, in Physical Review Letters
Abstract: The application of ac electric fields in aqueous suspensions of anisotropic particles leads to unbalanced liquid flows and nonlinear, induced-charge electrophoretic motion. We report experimental observations of the motion of Janus microparticles with one dielectric and one metal-coated hemisphere induced by uniform fields of frequency 100Hz-10kHz in NaCl solutions. The motion is perpendicular to the field axis and persists after particles are attracted to a glass wall. This phenomenon may find application in microactuators, microsensors and microfluidic devices.
Source: Dr. Orlin Velev
North Carolina State University